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    許紹君 Shao-Chun, Peggy, Hsu

    台大醫學院研發分處 第一共同研究室 助研究專家 Assistant Research Scientist

    信箱: peggyschsu@ntu.edu.tw, 電話: 886-2-23123456-88509

    位置: R1448, 基醫大樓

    GitHub: https://github.com/peggyscshu

    ORCID: https://orcid.org/0000-0002-6995-9338

    LAB: NTU Imaging core

     YouTube: NTU Imaging core

  • My business is

    taking care of your imaging data.

    Pipeline of imaging experiment + Image acquisition + Image analysis

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    Pipeline of Imaging Experiment

    Design

    Provide consultation on microscope related experimental design in sample preparation, group setup, image acquisition and analysis.

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    Image Acquisition

    Investigate

    Providing training course on the application of advanced microscopes including

    laser scanning microscope (LSM), 

    spinning disc microscope (SD),

    total internal reflection fluorescence microscope (TIRF), live cell imaging,

    super resolution microscope (AiryScan, STED), fluorescence lifetime imaging microscope (FLIM),

    laser dissection microscope (LDM),

    multiphoton application (MP), and

    high content screen (HCS).

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    Image Analysis

    Quantification and Visualization

    1. Providing training course of image analysis packages

    including Fiji, MetaMorph, Imaris, Amra, Zen, LASX

    and AxioVision.

    2. Image and data analysis automation.
    3. Design and compile customized scripts for specific application of image analysis with Fiji, MetaMorph and Amira.
    4. Design and compile customized scripts for the associated data analysis with Python, VBA and KNIME.

  • Experience

    2021 May ~ Present                                                               助研究專家 Assistant Research Scientist, National Taiwan University

    2015 Mar ~ 2021 May                               特殊技術人員 Research Technical Employee, Imaging Core, ICOB, Academia Sinica

    2013 Sept ~ 2015 Mar                                                      博士後研究員 PostDoc Fellow, Imaging Core, ICOB, Academia Sinica

    2004 Feb ~ 2006 Jul                                                                    應用工程師 Application Specialist, Taiwan Instrument Co., Ltd. 

    2003 Aug ~ 2004 Jan                                                                                  應用工程師 Application Specialist, Bio-Stem Co., Ltd.

    Education

    2006 Sept ~ 2013 Aug                                                  博士學程學位 Ph.D, Molecular Medicine Program, IBMS, Academia Sinica

    2006 Sept ~ 2013 Aug                  博士學位 Ph.D, Institute of Biochemistry and Molecular Biology, National Yang-Ming University

    2001 Sept ~ 2003 Jul                                                 碩士學程學位 M.S., Developmental Biology Program, IMB, Academia Sinica

    2001 Sept ~ 2003 Jul                                                               碩士學位 M.S., Institute of Genetics, National Yang-Ming University

    1997 Sept ~ 2001 Aug                                           學士學位 B.S., Department of Agriculture Chemisty, National Taiwan University

    Publication

     

     

    1. Uday Kumar; Chun-Yi Fang; Hsiao-Yuh Roan; Shao-Chun Hsu; Chung-Han Wang; Chen-Hui Chen. Whole-body replacement of larval myofibers generates permanent adult myofibers in zebrafish. EMBO J, 43,3090 (2024).

    2. Han-Yi Chen, Wan-Chen Hsieh, Yu-Chieh Liu, Huei-Ying Li, Po-Yo Liu, Yu-Ting Hsu, Shao-Chun Hsu, An-Chi Luo, Wei-Chen Kuo, Yi-Jhen Huang, Gan-Guang Liou, Meng-Yun Lin, Chun-Jung Ko, Hsing-Chen Tsai & Shu-Jung Chang Mitochondrial injury induced by a Salmonella genotoxin triggers the proinflammatory senescence-associated secretory phenotype. Nature Communications, 15, 2778 (2024).

    3. Ya-Han Chuang; Yueh-Feng Wu; Ya-Hui Lin; Yu-Xian Zhou; Shao-Chun Hsu; Sung-Jan Lin; Li-An Chu. Expansion microscopy for superresolution imaging of collagen-abundant tissues. Small Structures,2400231 (2024).

    4. You-An Su, Hsin-Yi Chiu , Yu-Chen Chang , Chieh-Ju Sung , Chih-Wei Chen ,Reika Tei , Xuang-Rong Huang , Shao-Chun Hsu , Shan-Shan Lin , Hsien-Chu Wang ,Yu-Chun Lin , Jui-Cheng Hsu , Hermann Bauer , Yuxi Feng , Jeremy M. Baskin ,Zee-Fen Chang , Ya-Wen Liu NME3 binds to phosphatidicacid and mediates PLD6-induced mitochondrial tethering J Cell Biol (2023) 222 (10): e202301091

    5. Chi‐Hung Lin; Tzu‐Yang Lin; Shao‐Chun Hsu; Hwei‐Jan Hsu. Expansion Microscopy‐based imaging for visualization of mitochondria in Drosophila ovarian germline stem cells. FEBS Open Bio 12,2102 (2022).

    6. Hem Kumar Tamang; Ruey‐Bing Yang; Zong‐Han Song; Shao‐Chun Hsu; Chien‐Chung Peng; Yi‐Chung Tung; Bing‐Hsiean Tzeng; Chien‐Chang Chen. Ca v 3.2 T‐type calcium channel regulates mouse platelet activation and arterial thrombosis. Journal of Thrombosis and Haemostasis, 00, 1 (2022).

    7. Keat Ying Chan, Ching-Cher Sanders Yan, Hsiao-Yuh Roan, Shao-Chun Hsu, Tzu-Lun Tseng, Chung-Der Hsiao, Chao-Ping Hsu & Chen-Hui Chen. Skin cells undergo asynthetic fission to expand body surfaces in zebrafish. Nature 605, 119 (2022).

    8. Min-ChenWang, Mao-TingHsu, Ching-ChunLin, Shao-ChunHsu, Ruo-DongChen, Jay-RonLee, Yi-LinChou, Hua-PinTseng, FumiyaFurukawa, Sheng-Ping L.Hwang, Pung-PungHwang, Yung-CheTseng. Adaptive metabolic responses in a thermostabilized environment: Transgenerational trade-off implications from tropical tilapia. Science of The Total Environment 806 (2022).

    9. Chieh-Ting Fang, Hsiao-Hui Kuo, Shao-Chun Hsu & Ling-Huei Yih. HSP70 regulates Eg5 distribution within the mitotic spindle and modulates the cytotoxicity of Eg5 inhibitors. Cell Death & Disease 11, 715 (2020).

    10. Oyundari Amartuvshin, Chi-Hung Lin, Shao-Chun Hsu, Shih-Han Kao, Alvin Chen, Wei-Chun Tang, Han-Lin Chou, Dong-Lin Chang, Yen-Yang Hsu, Bai-Shiou Hsiao, Elham Rastegari, Kun-Yang Lin, Yu-Ting Wang, Chi-Kuang Yao, Guang-Chao Chen, Bi-Chang Chen, Hwei-Jan Hsu. Aging shift mitochondrial dynamics toward fission to promote germline stem cell loss. Aging Cell 19, e13191 (2020).

    11. Chieh-Ting Fang, Hsiao-Hui Kuo, Shao-Chun Hsu, Ling-Huei Yih. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Division 14, 4 (2019).

    12. Shao-Chun Hsu, Ya-Ting Chang, Chien-Chang Chen. Early Growth Response 1 is an Early Signal Inducing Cav3.2 T-type Calcium Channels During Cardiac Hypertrophy. Cardiovascular Research 100, 222 (2013).

  • Contact Me

    歡迎各種回饋以及建議 關於高階光學顯微鏡、影像資料分析、機器學習、人工智慧以及資料科學，可以跟我說說你有興趣了解的議題，讓我們一起在這條路上探索學習!

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